The pre-cooling time is the time from starting the scalp cooling until a plateau in the temperature of the scalp skin is reached for most patients.
The post-cooling times per type of chemotherapy are unknown. We recommend post-cooling for 90 minutes (range 20-150 minutes). That is to say, after the administration of the last cytotoxic.
Exception: docetaxel 75 or 100 mg/m2 in a 3-week schedule (mono or combination with other agents). Research has only been done on post-cooling time for this schedule, and it appears that 20 minutes is sufficient.